Establish what you want to validate for each Cycle type

EXAMPLES

Egg freeze cycle

shouldn’t have data in columns for;

• sperm source

• insem data

• embryo data

• embryo transfer date

• pregnancy outcome

TX and cycle should be complete

Freeze all

shouldn’t have embryo transfer date

should have

• no embryo transfer as T

• freeze all as reason

• treatment & cycle complete

Egg recipient

• shouldn’t have egg collection date

IUI-D

• ensure that gamete source is donor

• ensure no lab events other than those for IUI

IVF

shouldn’t have any injected eggs

shouldn’t have ICSI practitioner

vice versa for ICSI

if 'Y' and ‘during down reg’

ensure;

reason is present in the data column

no egg collection date or future lab data

Tx completed is T

if ‘Y' and 'during stimulation’

ensure

• reason is entered

• no egg collection data or future lab data

• Tx completed is T

If if no egg collection date is present in the data column in any cycle

investigate is there actually was no egg collection, or if the lab events have just been forgotten

if no egg collection happened, cancel the cycle, enter a reason and complete the Tx.

if T in the data column

• ensure no ET date is present

• ensure no information about grades and numbers of embryos transferred is present

• Tx completed is T

If there is no ET date present

• ‘no embryos transferred column' should be T

• double check that the ‘embryo transfer’ lab event has not just been forgotten

• if truly no embryo transfer, ensure that all eggs and embryos have a fate in lab events, then tick no embryo transfer, give a reason and complete the cycle

if no embryos transferred is T in the data column,

• ensure that the reason given cross references with the lab events data

e.g. if reason is ‘no sperm available’ ensure that there is no insem data, fert check, embryo numbers etc'

failed fert

• no lab data further than discard after fert check, including any pregnancy data

• tx and cycle ticked as completed (T in the column)

if no eggs collected

check

• no lab data further than egg collection,

• no pregnancy results,

• tx and cycle ticked as completed (T in the column)

if egg collected number is zero

check

• that outcome column is no ET, and

• treatment and cycle are ticked as completed (T in the column)

if freeze all embryos

check

• no et date

• tx and cycle are ticked as completed (T in the column)

if a numbers is in the injected eggs column

check that the performed treatment is icsi

if a numbers is in the inseminated eggs column

check that the performed treatment is ivf

if there is a number in the injected eggs or inseminated eggs columns

check that there is a number in the ‘fertilised on Day 1’ column. Even a failed fertilisation will show a 0

(if not, you may have entered the fertilisation check mistakenly on Day 0 or Day 3

if gametes source is donor sperm

check

• there is no information in ejaculated date column

• there is a thaw date for semen

check there is a practitioner entered in all fields

Broadly review embryo grades for Embryo transfer and review against day of ET

check that the grade format corresponds with the day of transfer e.g for day 5 or 6 transfer, that the grades are in a format corresponding to blastocysts

if embryo transfer date entered

ensure;

pregnancy test result is present

if positive,

• that further outcome is present

• if ongoing, that live birth outcome is present

• if not ongoing, that TX and cycle completed

if negative,

• that no further outcome is present

• Tx and cycle completed

ensure all pregnancy-related outcomes have an embryo transfer date

if there are fetal hearts

ensure that outcome is ‘pregnant’ and that there is lab data

if the final outcome is live birth

ensure that;

there is a pregnant/not pregnant outcome

that there are fetal hearts and sacs recorded.

that the Tx and Cycle are completed